Skip to main content

This Week in PLOS: Mar 24, 2014

A PLOS One study by Norwegian researchers suggests metabolomic markers in blood and urine samples from pregnant women can help in predicting preeclampsia risk. Using a magnetic resonance-based metabolomics profiling approach, the team tested blood and urine samples from 10 pregnant women with preeclampsia, 10 unaffected pregnancies, and 10 age-matched women who were not pregnant. The search led to a set of nine metabolites in urine samples that were found at significantly different levels in women with preeclampsia. In the blood samples, meanwhile, the investigators picked up differences in high- and low-density lipoprotein levels in women with preeclampsia compared with those from both control groups. Our sister publication GenomeWeb Daily News has more on the study, here.

In another PLOS One study, a team from the University of Ottawa describes the dielectric breakdown method they've developed for creating and enlarging solid-state nanopores in a fast and cost-effective manner. The approach, which involves applying voltage across a membrane composed of insulating material until a single breakdown event occurs, was presented in Arxiv last fall. For more on the nanopore fabrication method and its potential applications, check out this story from our recent issue of In Sequence.

The Scan

UK Funds to Stay Ahead of Variants

The UK has announced a further £29.3 million to stay on top of SARS-CoV-2 variants, the Guardian reports.

Push for Access

In a letter, researchers in India seek easier access to COVID-19 data, Science reports.

Not as Cold

Late-stage trial results are expected soon for an RNA-based vaccine that could help meet global demand as it does not require very cold storage, the New York Times writes.

Genome Research Papers on Microbes' Effects on Host Transfer RNA, Honeybee Evolution, Single-Cell Histones

In Genome Research this week: influence of microbes on transfer RNA patterns, evolutionary relationships of honeybees, and more.