This Week in PLOS

Northwestern University's Serdar Bulun and colleagues used array-based methylation and gene expression profiling for a PLOS Genetics study aimed at identifying epigenetic shifts associated with endometriosis. By comparing endometriosis samples — the altered endometrial tissue that grows outside the uterus in affected individuals — with healthy endometrial tissue, the group narrowed in on more than 400 genes with disease-associated methylation and expression changes.

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