This Week in PLOS

In PLOS One, researchers from Georgetown University and elsewhere describe a set of frequently mutated and/or copy number altered genes associated with poor breast cancer outcomes. The team profiled ductal carcinoma in situ samples and took advantage of genomic data on infiltrating ductal carcinoma cases from the Cancer Genome Atlas, looking at the prevalence of cases involving loss or low levels of SYK — a gene suspected of contributing to immunity and cancer risk.

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This Week in PLOS

This Week in PLOS

This Week in PLOS

This Week in PLOS

This Week in PLOS

This Week in PLOS

The Guardian discusses whether big science projects are worth the loss of resources available for other scientific pursuits.

An NEJM update from the ClinVar team highlights the difficulties of interpreting genetic variants.

In Nature this week: genomic analysis of high-grade serous ovarian cancer, and more.

The new Riken president outlines some of his plans for the institute.