This Week in PLOS

In PLOS One, researchers from Georgetown University and elsewhere describe a set of frequently mutated and/or copy number altered genes associated with poor breast cancer outcomes. The team profiled ductal carcinoma in situ samples and took advantage of genomic data on infiltrating ductal carcinoma cases from the Cancer Genome Atlas, looking at the prevalence of cases involving loss or low levels of SYK — a gene suspected of contributing to immunity and cancer risk.

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This Week in PLOS

This Week in PLOS

This Week in PLOS

This Week in PLOS

This Week in PLOS

This Week in PLOS

In Science this week: swapping yeast genes with human orthologs to study conservation of function, and more.

Hong Kong is using DNA phenotyping to shame litterers.

A study appearing in Cell suggests some metastatic castration-resistant prostate cancer patients could benefit from PARP inhibitor therapy.

NIH's Francis Collins writes that scientific advances are poised to help populations all over the world, but more scientists are needed to keep the momentum.