This Week in PLOS

Pennsylvania State University's Marylyn Ritchie and her colleagues report in PLOS Genetics that the natural frequency of rare variants is a common confounder of genetic analyses. The researchers applied a collapsing method called BioBin to whole-genome population data from individuals from 1000 Genomes Project Phase I data to search for aggregate differences in low frequency variation between populations.

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Helix customers can purchase apps that interpret different aspects of their genome, Technology Review reports.

The New York Times reports that a number of companies and research institutes are pursuing gene therapies.

Salmon with shorter telomeres survive to make the trip back to their river homes, New Scientist reports.

In PLOS this week: vaginal microbiome composition, population patterns of Chagas-carrying Rhodnius ecuadoriensis, and more.