This Week in PLOS

Pennsylvania State University's Marylyn Ritchie and her colleagues report in PLOS Genetics that the natural frequency of rare variants is a common confounder of genetic analyses. The researchers applied a collapsing method called BioBin to whole-genome population data from individuals from 1000 Genomes Project Phase I data to search for aggregate differences in low frequency variation between populations.

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In PLOS this week: genes under positive selection in Plasmodium falciparum populations, genetic variation in Epstein-Barr viruses, and more.

Cancer clinical trial patients settle with Anil Potti and Duke University.

A trio of researchers is trying to raise money to sequence and analyze the genome of a cat with a suite of unusual traits.

Two Johns Hopkins researchers discuss the need for evidence-based data analysis.