This Week in PLOS

Researchers from Portugal, reporting in PLOS Pathogens, used genome sequencing as part of their effort to understand adaptations leading to pathogenesis in Escherichia coli. Together with mathematical modeling and experiments gauging the bug's evolution and physical features, the team's genome sequence assessments suggested that the presence or absence of a lone transposable element can spell the difference between commensal and virulent E.

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Under a proposed spending bill, the US National Institutes of Health would see an additional $3 billion in funding.

Researchers from the University of Oxford and the University of Sydney sequenced numerous platypus genomes to study their population history.

Robert Redfield, the new pick to lead the US Centers for Disease Control and Prevention, has faced criticism for some of his work.

In Nature this week: sequenced genomes of five additional Neanderthals, and more.