This Week in PLOS

In PLOS Medicine, researchers from the US and Finland describe blood transcriptional signatures corresponding to respiratory syncytial virus infection and severity in infants. The expression patterns — identified using array-based analyses on blood samples from groups of American and Finnish infants with RSV — appear capable of distinguishing RSV from other forms of lower respiratory tract infection and finding those at risk of developing severe RSV infections.

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Rare gene mutations are guiding the search for drugs to manage chronic pain without opioids, according to CNBC.

The new Francis Crick Institute building can get too noisy for some researchers to concentrate, according to the Guardian.

CBS News reports that there are still many vacancies at the White House Office of Science and Technology Policy, but that it's uncertain whether they will be filled.

In Nucleic Acids Research this week: pipeline to analyze and visualize bacterial genomes, database of global set of human genomes, and more.