This Week in PLOS

In PLOS Genetics, researchers from Germany, the US, and Spain report on fungal evolutionary patterns gleaned through genome and transcriptome sequencing on Pyronema confluens, a filamentous fungal species from the same lineage as the black truffle. The team unearthed some 13,400 predicted protein-coding genes in the 50 million base P. confluens genome assembled for the study.

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Microsoft co-founder Paul Allen also contributed to brain research, NPR reports.

The New York Times reports on the shifting interpretations of what some genetic variants mean over time.

In Cell this week: investigation of metastatic tumor evolution, more than 16,000 genetic variants introduced into the budding yeast model organism, and more.

MIT's Technology Review reports on Genentech's pursuit of personalized cancer vaccines.