This Week in PLOS

In PLOS Genetics, Duke University's David Goldstein and colleagues from the US and Australia present a scheme for interpreting information in personal genomes. With the help of 6,500 exomes sequenced through the National Heart, Lung, and Blood Institute's Exome Sequencing Project, the group came up with a so-called intolerance scoring system that quantifies the functional variation found in genes relative to their typical level of tolerance to such variability.

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An Australian-led team has generated a draft genome assembly of the invasive cane toad in hopes it will help in population control, the Sydney Morning Herald reports.

The New York Times reports that the US Department of Defense has implemented about half the recommendations made to improve safe handling of dangerous agents.

In PLOS this week: approach for teasing out archaic introgression in human genomes, immune transcription features in HCV infection, and more.

Stat News reports that Maryland is promoting itself to the biotech industry with a mobile billboard.