This Week in PLOS

In PLOS Genetics, Duke University's David Goldstein and colleagues from the US and Australia present a scheme for interpreting information in personal genomes. With the help of 6,500 exomes sequenced through the National Heart, Lung, and Blood Institute's Exome Sequencing Project, the group came up with a so-called intolerance scoring system that quantifies the functional variation found in genes relative to their typical level of tolerance to such variability.

Get the full story

This story is free
for registered users

Registering provides access to this and other free content.

Register now.

Already have an account?
Login Now.

A research duo estimates in PLOS One the number of papers that have used misidentified cell lines.

UK's National Institute for Health and Care Excellence approves GlaxoSmithKline's SCID gene therapy despite cost.

Science reports that Brazilian researchers are petitioning for the reversal of budget cuts.

In PLOS this week: gene flow patterns in common ash, guidelines for using morpholinos in zebrafish, and more.