This Week in PLOS

A study in PLOS Genetics looks at how an individual's genetic background affects the phenotype elicited by various genetic alterations. Using a genome-wide screen for modifiers of a wing-related allele in two Drosophila melanogaster genetic backgrounds, Michigan State University researchers found that almost three-quarters of the modifiers identified had variable effects depending on the broader genetic background.

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Two researchers have found that behavioral genetic defenses in criminal cases don't tend to affect outcomes, according to Popular Science.

Researchers report that while host genetics influence the oral microbiome, they don't appear to affect cavity-causing microbes, the Economist says.

Pandas' gut microbiomes change as what they eat changes with the seasons, writes Discover's Inkfish blog.

In PLOS this week: comparative genomic study of malaria-linked macaque parasite, search for apple root reference genes, and more.