This Week in PLOS

A study in PLOS Genetics looks at how an individual's genetic background affects the phenotype elicited by various genetic alterations. Using a genome-wide screen for modifiers of a wing-related allele in two Drosophila melanogaster genetic backgrounds, Michigan State University researchers found that almost three-quarters of the modifiers identified had variable effects depending on the broader genetic background.

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This Week in PLOS

This Week in PLOS

This Week in PLOS

This Week in PLOS

This Week in PLOS

This Week in Science

In Science this week: mtDNA analysis give glimpse into decline of Neanderthals in Europe, and more.

The University of Arizona's Raina Maier writes that an understanding of the Earth's microbiome is needed.

The proposed Canadian budget emphasizes partnerships with industry, Nature News reports.

An Australian study of personalized medicine has run into problems as it recruits patients.