This Week in PLOS

A study by researchers from Sweden, the US, and elsewhere in PLOS Genetics looks at obesity in light of both genetic and physical activity contributors. Using self-reported physical activity data for 111,421 individuals of European ancestry whose genotype at a dozen obesity-related risk loci had been directly assessed or imputed, the group did a gene-by-activity analysis aimed at understanding whether high levels of activity can dial back genetic obesity risk.

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CNN reports that researchers have tied a new variant to opioid addiction risk.

Organoids derived from patients' tumors may help determine what chemotherapy treatment patients would benefit from, according to New Scientist.

An initiative from GenomeAsia 100K hopes to increase the number of South Asians in genetic research, according to NBC News.

In Science this week: genomic analysis of ancient and modern horses indicates population turnover, and more.