This Week in PLOS

Researchers from Sweden and Australia looked at methylation shifts in adipose tissue from dozens of men embarking on a six-month exercise regimen — work that they describe in PLOS Genetics. Using array-based approaches, the team assessed methylation patterns across the genome in 31 healthy men — 15 with a family history of diabetes and 16 without — who initially reported low levels of physical activity.

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In an against-all-odds twist, a researcher studying exceeding rare FOXG1 mutations discovers her daughter has the syndrome.

An effort by Genomics Medicine Ireland is creating a database of diseases based on the genomics of people in Ireland. It now is looking into the possibility of including Scotland in its work.

In recent weeks, the direct-to-consumer genetics firm has rolled out a health hub where customers can share information concerning 18 common health conditions.

In PLOS this week, new genes associated with prostate cancer risk, genetic patterns in M. bovis, and more.