A number of microRNAs can repress translation of Twist1, a proto-oncogene whose upregulation is linked to resistance to cancer drugs, report Aarhus University researchers in PLOS One. In a number of cell lines, the researchers found that miR-145a-5p, miR-151-5p and a combination of miR-145a-5p and miR-151-5p or of miR-151-5p and miR-337-3p could repress the expression of the oncogene.
Get the full story
This story is free
for registered users
Registering provides access to this and other free content.
Register now.Already have an account?
Login Now.