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In PLoS Biology this week, researchers study canalization, or the reduction in phenotypic variation, in developing Drosophila embryos. They used a predictive dynamical model of gene regulation to study the effect of variation of the maternal protein, Bicoid, on downstream gap genes, showing that canalization results from specific interactions among these genes. In embryos mutant for two gap genes, Krüppel and knirps, variation is increased.

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In Science this week: set of 64 haplotype assemblies from 32 individuals, and more.