This Week in PLoS

In PLoS Biology this week, researchers study canalization, or the reduction in phenotypic variation, in developing Drosophila embryos. They used a predictive dynamical model of gene regulation to study the effect of variation of the maternal protein, Bicoid, on downstream gap genes, showing that canalization results from specific interactions among these genes. In embryos mutant for two gap genes, Krüppel and knirps, variation is increased.

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Robert Redfield is floated as the next director of the US Centers for Disease Control and Prevention, the Washington Post reports.

The New York Times writes that the National Institutes of Health's All of Us Research Program is "ambitious" and that some are concerned it might be overly so.

Representative Lamar Smith's criticism of the National Science Foundation has "changed the nature of the conversation," according to ScienceInsider.

In PLOS this week: non-coding RNA function in yeast, transcriptomic profiles of malaria parasites, and more.