This Week in PLoS

In PLoS Biology this week, researchers study canalization, or the reduction in phenotypic variation, in developing Drosophila embryos. They used a predictive dynamical model of gene regulation to study the effect of variation of the maternal protein, Bicoid, on downstream gap genes, showing that canalization results from specific interactions among these genes. In embryos mutant for two gap genes, Krüppel and knirps, variation is increased.

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The apple has traveled westward and eastward along the Silk Road, according to a new genetic analysis.

In Nature this week: GWAS data used to reposition drugs for psychiatric use, and more.

Genetic disease risk information doesn't always spur people to make healthy lifestyle changes, according to the Associated Press.

A University of California, San Diego-led team has used liquid biopsies to uncover possible treatments for patients with cancers of unknown primary.