This Week in PLOS

In PLOS One, researchers from the University of Massachusetts at Amherst and the University of Pennsylvania report on an analytical technique known as "mixed modeling of meta-analysis p-values," or MixMAP. The statistical method is designed to unearth associations at the locus level from existing data from genome-wide association studies, they say, by taking into account both SNP-level associations and genome structure.

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Technology Review reports that researchers in the US have used CRISPR to modify a number of human embryos.

By introducing genes from butterfly peas and Canterbury bells, researchers in Japan have developed a blue chrysanthemum, according to NPR.

Plant researchers plan to sequence some 10,000 samples that represent the major plant clades, ScienceInsider reports.

In Nature this week: a Danish reference genome, and more.