This Week in PLOS

In PLOS Genetics, an international research group delves into the genetics of chronic pain. After using a heat test to quantify pain susceptibility in more than 2,500 TwinsUK project participants, investigators did exome sequencing on a few hundred women from the cohort's pain-sensitive and -insensitive extremes: 203 pain-sensitive or insensitive individuals from TwinsUK1 and 210 pain-prone or tolerant women from the study's second phase.

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This Week in PLOS

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In Genome Research this week: mitochondrial and nuclear gene fusions in cancer, role of genomic imprinting in tissue-specific gene expression, and more.

Maria Freire from the Foundation for the NIH calls for "politically popular pledges of support" for the NIH to turn into support for increased funding for the agency.

A Thomson Reuters analysis indicates that the life sciences, rather than the tech sector, are increasingly driving global innovation.

The White House says ethical discussions about genome editing of the human germline are needed.