This Week in PLOS

In PLOS Genetics, an international research group delves into the genetics of chronic pain. After using a heat test to quantify pain susceptibility in more than 2,500 TwinsUK project participants, investigators did exome sequencing on a few hundred women from the cohort's pain-sensitive and -insensitive extremes: 203 pain-sensitive or insensitive individuals from TwinsUK1 and 210 pain-prone or tolerant women from the study's second phase.

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