This Week in PLOS

In PLOS One, researchers from Estonia, the US, and Canada describe placental gene expression profiles that seem to be associated with complications such as preeclampsia or gestational diabetes during pregnancy. Using array-based approaches to look at the levels of around 47,000 transcripts in placental tissue from early or mid-gestation, the team tracked down more than genes showing transcriptional shifts at mid-gestation.

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A fire at a Manchester hospital may have destroyed lab equipment and data, the Guardian reports.

Researchers generate a genetic database from skeletal remains from the 1845 Franklin Expedition to the Arctic, Live Science reports.

Researchers in China have begun another trial using CRISPR/Cas9 approaches in cancer patients, according to the Wall Street Journal.

In Science this week: human DNA found in sediments from archeological sites lacking bones, and more.