This Week in PLoS

Scientists have published work this week in PLoS Biology looking at genetic switches and gene expression related to cell fate. They used a "classic bistable memory module" to find transcription errors, using the lac operon in E. coli as a positive feedback loop. Using single cell analysis, they showed that when transcriptional fidelity decreases, the frequency of epigenetic switching from one state of expression to the other is increased.

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Researchers have sequenced the northern white rhinoceros to gauge whether it could be brought back from the edge of extinction, the New York Times reports.

Bavaria expands its forensic genetic analyses to include DNA phenotyping, raising discrimination concerns.

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