This Week in PLOS

In PLOS One, Translational Genomics Research Institute researcher Daniel Von Hoff and his colleagues describe findings from a whole-genome sequencing study of pancreatic cancer. The group, which included investigators from TGen, Scottsdale's Mayo Clinic, the Virginia G. Piper Cancer Center Clinical Trials, and Arizona State University, sequenced matched tumor and normal samples from three individuals with pancreatic adenocarcinoma.

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The US Food and Drug Administration has approved Kite Pharmaceuticals' CAR T-cell therapy for large B-cell lymphomas, the New York Times reports.

Kaiser Health News reports that gene therapies could cost more than a million dollars.

Worcester Polytechnic Institute researchers have received a grant to combine biology and computer science for high school students.

In Nature this week: variants associated with obsessive-compulsive disorder, review of key CRISPR enzymes, and more.