This Week in PLoS

A group of researchers report in PLoS Biology that Mycobacterium tuberculosis strains that affect people are more genetically diverse than had been assumed. They studied 7 megabase pairs of DNA sequence data from 108 strains of M. tuberculosis and attribute the diversity to human demographic and migratory events. The authors also say that current human population trends, global travel, urbanization, and population growth, may be contributing to the spread of drug-resistant tuberculosis

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Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.

The Wall Street Journal looks into the cost of new gene therapies.

An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.