This Week in PLoS

Researchers at Stanford University School of Medicine present in PLoS Computational Biology this week an integrative method for the data-driven discovery of candidate genes for human pain sensitivity that takes "advantage of the vast amount of existing disease-related clinical literature and gene expression microarray data stored in large international repositories." To develop this, the researchers first ranked thousands of diseases according to their disease-specific pai

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Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.

An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.

The Wall Street Journal looks into the cost of new gene therapies.

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.