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This Week in PLoS

In PLoS Biology this week, investigators at MD Anderson Cancer Center and their collaborators show that "p53 plays an active role in promoting differentiation of human embryonic stem cells and opposing self-renewal by regulation of specific target genes and microRNAs." Further, the team writes, "p53 activates expression of miR-34a and miR-145, which in turn repress stem cell factors OCT4, KLF4, LIN28A, and SOX2 and prevent backsliding to pluripotency." and This study "under

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Bloomberg reports that the DNA-for-cash deal reported in Kentucky might be a more widespread scam.

St. Jude Children's Research Hospital scientists have treated infants with X-linked severe combined immunodeficiency using gene therapy in an early phase study.

St. Louis Public Radio reports that some African Americans are turning to DNA ancestry testing to help guide genealogical searches.

In Nature this week: a genomic analysis of the snailfish Pseudoliparis swirei, ancient DNA analysis gives insight into the introduction of farming to England, and more.