This Week in PLoS

University of Alabama at Birmingham's Degui Zhi and Rui Chen at Baylor College of Medicine in Houston, Texas, this week "present a statistical modeling framework to calculate the power [and] the probability of identifying truly disease-causing genes" when performing mutation detection studies on rare monogenic Mendelian diseases using exome sequencing.

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Researchers find that a personalized medicine approach could help people who experience pain while taking statins, New Scientist reports.

US National Science Foundation is continuing its responsible research conduct training policy despite its flaws, ScienceInsider reports.

A CRISPR-themed meeting explored how the tool could and should be used, Wired reports.

In Science this week: database of proteins' effects on cancer, targeted error correction sequencing, and more.