This Week in PLoS

In PLoS Biology this week, a team led by investigators at the State University of Campinasi in Brazil uses metagenomics to show that the presence of gut microbiota in TLR2-deficient mice — which, "under germ-free conditions, are protected from diet-induced insulin resistance" — could reverse the animal's phenotype by inducing insulin resistance.

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CNN reports that researchers have tied a new variant to opioid addiction risk.

Organoids derived from patients' tumors may help determine what chemotherapy treatment patients would benefit from, according to New Scientist.

An initiative from GenomeAsia 100K hopes to increase the number of South Asians in genetic research, according to NBC News.

In Science this week: genomic analysis of ancient and modern horses indicates population turnover, and more.