This Week in PLoS

In a paper published online in advance in PLoS Genetics this week, investigators at the National Institute on Deafness and Other Communication Disorders and elsewhere show that "a non-coding point mutation of Zeb1 causes multiple developmental malformations and obesity in twirler mice." The team says this mutation "acts via a gain-of-function to disrupt regulation of Zeb1Tw expression, epithelial-mesenchymal cell fate or interactions, and structural development of the inner ear in Twirler mice." The authors add that "this is a novel mechanism

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Researchers find that a personalized medicine approach could help people who experience pain while taking statins, New Scientist reports.

US National Science Foundation is continuing its responsible research conduct training policy despite its flaws, ScienceInsider reports.

A CRISPR-themed meeting explored how the tool could and should be used, Wired reports.

In Science this week: database of proteins' effects on cancer, targeted error correction sequencing, and more.