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In a paper published online in advance in PLoS Genetics this week, investigators at the National Institute on Deafness and Other Communication Disorders and elsewhere show that "a non-coding point mutation of Zeb1 causes multiple developmental malformations and obesity in twirler mice." The team says this mutation "acts via a gain-of-function to disrupt regulation of Zeb1Tw expression, epithelial-mesenchymal cell fate or interactions, and structural development of the inner ear in Twirler mice." The authors add that "this is a novel mechanism

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NPR reports that some insect pests are now becoming resistant to Bt crops.

A 50-year-old cold case was cracked using genetic genealogy, the New York Times reports.

Science reports the US Food and Drug Administration did not consult an outside panel in its approval of remdesivir as a COVID-19 treatment.

In Nature this week: a framework for future human genomic research, PORE-cupine approach to study RNA structure using nanopore sequencing, and more.