This Week in PLoS

In a paper published online in advance in PLoS Genetics this week, investigators at the National Institute on Deafness and Other Communication Disorders and elsewhere show that "a non-coding point mutation of Zeb1 causes multiple developmental malformations and obesity in twirler mice." The team says this mutation "acts via a gain-of-function to disrupt regulation of Zeb1Tw expression, epithelial-mesenchymal cell fate or interactions, and structural development of the inner ear in Twirler mice." The authors add that "this is a novel mechanism

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In Science this week: International Wheat Genome Sequencing Consortium publishes the bread wheat cultivar Chinese Spring reference genome, and more.

At his FDA Law Blog, Jeffrey Gibbs discusses FDA's technical assistance for the draft Diagnostic Accuracy and Innovation Act.

The New York Times reports that genetic testing has uncovered unfaithful penguins at a Utah aquarium.

Cancer researcher loses funding under new Wellcome Trust anti-bullying policies, the Guardian reports.