This Week in PLoS

In a paper published online in advance in PLoS Genetics this week, investigators at the National Institute on Deafness and Other Communication Disorders and elsewhere show that "a non-coding point mutation of Zeb1 causes multiple developmental malformations and obesity in twirler mice." The team says this mutation "acts via a gain-of-function to disrupt regulation of Zeb1Tw expression, epithelial-mesenchymal cell fate or interactions, and structural development of the inner ear in Twirler mice." The authors add that "this is a novel mechanism

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An artificial intelligence-based analysis suggests a third group of ancient hominins likely interbred with human ancestors, according to Popular Mechanics.

In Science this week: reduction in bee phylogenetic diversity, and more.

The New York Times Magazine looks into paleogenomics and how it is revising what's know about human history, but also possibly ignoring lessons learned by archaeologists.

The Economist reports on Synthorx's efforts to use expanded DNA bases they generated to develop a new cancer drug.