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In PLoS Genetics this week, researchers at the University of Montreal report on their investigation of “age-dependent recombination rates in human pedigrees,” in which they found a previously unreported “significant decrease in recombination rates with advancing maternal age.” The Montreal team says this effect seems to be localized, and may be in part “responsible for the higher rates of aneuploidy in older women.”

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The UK and the European Union have come to a sticking point in the negotiation of how the UK might remain involved in the Horizon Europe research program, the Guardian reports.

The New York Times reports that experts pushed during a meeting of an FDA advisory board for the agency to require more safety data from SARS-CoV-2 vaccine trials.

The Washington Post reports Moderna expects that it will have enough data on its candidate SARS-CoV-2 vaccine to submit to regulatory authorities by mid-November.

In Science this week: ANXA11 variants affect calcium homeostasis and stress granule disassembly in ALS, and more.