This Week in PLoS

An international team of scientists used chIP-on-chip to map the chromosomal distribution of Drosophila Polycomb group (PcG) proteins, the N- and C-terminal fragments of the Trithorax (TRX) protein, and four candidate DNA-binding factors for PcG recruitment. They also mapped histone modifications associated with PcG-dependent silencing and TRX-mediated activation.

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The UK's Nuffield Council on Bioethics says genetically modifying human embryos could be morally permissible, according to the Guardian.

A new Nature Biotechnology paper reports that CRISPR-Cas9 gene editing can lead to large deletions or complex rearrangements that could be pathogenic.

The Wall Street Journal likens a prototype developed by Synthetic Genomics to a "biological fax machine."

In PNAS this week: strategy for reactivating Rett syndrome-linked MECP2, small molecules able to suppress Staphylococcus aureus virulence, and more.