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This week in PLoS Computational Biology, the University of Copenhagen's Jan Gorodkin and Ivo Hofacker discuss the "basic principles of RNA folding" as well as how genomic screens for de novo RNA structures have been used to interrogate regulatory RNA structure on mRNAS and novel non-coding RNA genes, among other things.

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Researchers are developing a breath test to determine how severe patients' methylmalonic acidemia disease is, FierceBiotech reports.

NPR reports that vaccine developers are working on SARS-CoV-2 vaccines that are easier to store or administer than the current crop.

Reuters reports that France is to recommend that people under 55 who received one dose of AstraZeneca's SARS-CoV-2 vaccine receive a different vaccine for their second dose.