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This Week in PLoS

This week in PLoS Genetics, investigators at the University of Michigan describe the "pathogenic mechanism of the FIG4 mutation responsible for Charcot-Marie-Tooth disease CMT4J." In developing a mouse model of this severe form of Charcot-Marie-Tooth neuropathy "by expressing a Fig4-I41T cDNA transgene on the Fig4 null background," the team found that "FIG4-I41T is a hypomorphic allele encoding a protein that is unstable in vivo … suggesting that patients with CMT

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Two researchers are calling for education for scientists on defending facts.

Researchers were among those who marched in London this weekend to call for another vote on Brexit.

Duke has agreed to pay $112.5 million to settle a lawsuit regarding its handling of data falsified by biologist Erin Potts-Kant. 

In PLOS this week: genetic factors influencing inorganic arsenic metabolism and toxicity, a germline variant in the cell adhesion molecule-coding gene DSCAM, and more.