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This week in PLoS Genetics, investigators at the University of Michigan describe the "pathogenic mechanism of the FIG4 mutation responsible for Charcot-Marie-Tooth disease CMT4J." In developing a mouse model of this severe form of Charcot-Marie-Tooth neuropathy "by expressing a Fig4-I41T cDNA transgene on the Fig4 null background," the team found that "FIG4-I41T is a hypomorphic allele encoding a protein that is unstable in vivo … suggesting that patients with CMT

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A UK study on mixing SARS-CoV-2 vaccines is expanding to include vaccines developed by additional companies, according to the Guardian.

According to Science, the US National Academy of Sciences is poised to eject two members accused of sexual harassment.

In Nucleic Acids Research this week: machine learning approach to detect DNA-bound proteins, CRISPR-based method for activating specific gene targets, and more.

The FDA and CDC call for a pause in administering Johnson & Johnson's SARS-CoV-2 vaccine while reports of rare blood clots are looked into, reports the Wall Street Journal.