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In PLoS Biology this week, members of the Encyclopedia of DNA Elements — or ENCODE — Project Consortium present an overview of the initiative in the form of a user's guide. The group hopes the guide will "facilitate the interpretation of the human genome" using ENCODE data.

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Researchers are developing a breath test to determine how severe patients' methylmalonic acidemia disease is, FierceBiotech reports.

NPR reports that vaccine developers are working on SARS-CoV-2 vaccines that are easier to store or administer than the current crop.

Reuters reports that France is to recommend that people under 55 who received one dose of AstraZeneca's SARS-CoV-2 vaccine receive a different vaccine for their second dose.