This Week in PLoS

In PLoS Computational Biology this week, a trio of investigators at Portugal's Instituto Gulbenkian de Ciência demonstrate that genetic redundancy is lost as a result of decreased selection for robustness in predicable environments. In interrogating "the evolutionary dynamics of genetic redundancy in extremely reduced genomes," the team found "a selective drive to keep the diversity of protein families while sacrificing paralogy."

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Microsoft co-founder Paul Allen also contributed to brain research, NPR reports.

The New York Times reports on the shifting interpretations of what some genetic variants mean over time.

In Cell this week: investigation of metastatic tumor evolution, more than 16,000 genetic variants introduced into the budding yeast model organism, and more.

MIT's Technology Review reports on Genentech's pursuit of personalized cancer vaccines.