This Week in PLoS

In PLoS One this week, a research team led by investigators at the University of Maryland School of Medicine show that polymorphisms of CYP19A1, a gene that encodes aromatase, "are associated with survival among patients with cardiovascular disease in a sex-specific manner." In case-control studies, the Maryland-led team genotyped participants for six CYP19A1 SNPs. For one SNP in particular — -81371 C — the team observed a 78 percent increase in mortality for men with acute coronary syndrome, as compared with affected women. The authors say that theirs is the first "study ...

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A fire at a Manchester hospital may have destroyed lab equipment and data, the Guardian reports.

Researchers generate a genetic database from skeletal remains from the 1845 Franklin Expedition to the Arctic, Live Science reports.

Researchers in China have begun another trial using CRISPR/Cas9 approaches in cancer patients, according to the Wall Street Journal.

In Science this week: human DNA found in sediments from archeological sites lacking bones, and more.