This Week in PLoS | GenomeWeb

This Week in PLoS

In PLoS Genetics this week, a team of investigators led by researchers at the Washington University School of Medicine report that rs1868402, a SNP in the gene encoding the regulatory sub-unit of protein phosphatase B, is associated with cerebrospinal fluid ptau181 levels, and therefore "rate of decline in Alzheimer's disease." The team's "analyses suggest that genetic variants associated with CSF ptau181 levels may have a greater impact on rate of progression, while genetic variants such as APOE4, that are associated with CSF Aβ42 levels influence risk and onset but not the rate o

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In Science this week: metagenomic-based technique for determining protein structure, and more.

An academic laments the rise of narcissism in the sciences, the Guardian reports.

Outgoing FDA commissioner Robert Califf writes in an editorial that the agency can help boost innovation.

The Trump transition team has asked NIH Director Francis Collins to remain at his post, though it's unclear for how long that will be.