This Week in PLoS

In PLoS Genetics this week, a team of investigators led by researchers at the Washington University School of Medicine report that rs1868402, a SNP in the gene encoding the regulatory sub-unit of protein phosphatase B, is associated with cerebrospinal fluid ptau181 levels, and therefore "rate of decline in Alzheimer's disease." The team's "analyses suggest that genetic variants associated with CSF ptau181 levels may have a greater impact on rate of progression, while genetic variants such as APOE4, that are associated with CSF Aβ42 levels influence risk and onset but not the rate o

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CNN reports that researchers have tied a new variant to opioid addiction risk.

Organoids derived from patients' tumors may help determine what chemotherapy treatment patients would benefit from, according to New Scientist.

An initiative from GenomeAsia 100K hopes to increase the number of South Asians in genetic research, according to NBC News.

In Science this week: genomic analysis of ancient and modern horses indicates population turnover, and more.