This Week in PLoS

In PLoS Genetics this week, a team of investigators led by researchers at the Washington University School of Medicine report that rs1868402, a SNP in the gene encoding the regulatory sub-unit of protein phosphatase B, is associated with cerebrospinal fluid ptau181 levels, and therefore "rate of decline in Alzheimer's disease." The team's "analyses suggest that genetic variants associated with CSF ptau181 levels may have a greater impact on rate of progression, while genetic variants such as APOE4, that are associated with CSF Aβ42 levels influence risk and onset but not the rate o

Get the full story

This story is free
for registered users

Registering provides access to this and other free content.

Register now.

Already have an account?
Login Now.

Researchers find that a personalized medicine approach could help people who experience pain while taking statins, New Scientist reports.

US National Science Foundation is continuing its responsible research conduct training policy despite its flaws, ScienceInsider reports.

A CRISPR-themed meeting explored how the tool could and should be used, Wired reports.

In Science this week: database of proteins' effects on cancer, targeted error correction sequencing, and more.