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In PLoS Biology this week, a team led by investigators at Harvard reports that the TRIM5 gene suppresses cross-species transmission of simian immunodeficiency viruses of sooty mangabeys "and selects for emergence of resistant variants." The team analyzed cross-species transmission of SIVsm in two groups of rhesus macaques and "found a significant effect of TRIM5 genotype on viral replication levels." In SIVsmE543-3-infected animals, the "TRIM5 genotype correlated with approx

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NPR reports that vaccine developers are working on SARS-CoV-2 vaccines that are easier to store or administer than the current crop.

Researchers are developing a breath test to determine how severe patients' methylmalonic acidemia disease is, FierceBiotech reports.

Reuters reports that France is to recommend that people under 55 who received one dose of AstraZeneca's SARS-CoV-2 vaccine receive a different vaccine for their second dose.