This Week in PLoS

Scientists publishing in PLoS Biology this week have used stable isotope labeling with amino acids in cell culture (SILAC) and subsequent mass spec to screen the human proteome for possible targets of γ-secretase and found a small number of new substrates, all of which are type I transmembrane proteins with diverse biological roles.

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Researchers describe a way to share data while keeping it secure, Agence France Presse reports.

In Science this week: genetic mutations typically associated with esophageal cancer are common in older, healthy individuals, and more.

India's Council of Scientific and Industrial Research has a new director-general, according to ScienceInsider.

A new study links more than a hundred genes to autism spectrum disorder, Discover's D-brief blog reports.