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This Week in PLoS

Scientists publishing in PLoS Biology this week have used stable isotope labeling with amino acids in cell culture (SILAC) and subsequent mass spec to screen the human proteome for possible targets of γ-secretase and found a small number of new substrates, all of which are type I transmembrane proteins with diverse biological roles.

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Bloomberg reports that the DNA-for-cash deal reported in Kentucky might be a more widespread scam.

St. Jude Children's Research Hospital scientists have treated infants with X-linked severe combined immunodeficiency using gene therapy in an early phase study.

St. Louis Public Radio reports that some African Americans are turning to DNA ancestry testing to help guide genealogical searches.

In Nature this week: a genomic analysis of the snailfish Pseudoliparis swirei, ancient DNA analysis gives insight into the introduction of farming to England, and more.