In a paper published online in advance in Nucleic Acids Research this week, researchers at Israel's Weizmann Institute of Science and Tel Aviv University show that a "lack of co-adaptation between the codon usage of the transferred gene and the tRNA pool of the recipient organism" is a previously unrecognized central barrier to horizontal gene transfer between microbes.

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In Science this week: International Wheat Genome Sequencing Consortium publishes the bread wheat cultivar Chinese Spring reference genome, and more.

At his FDA Law Blog, Jeffrey Gibbs discusses FDA's technical assistance for the draft Diagnostic Accuracy and Innovation Act.

The New York Times reports that genetic testing has uncovered unfaithful penguins at a Utah aquarium.

Cancer researcher loses funding under new Wellcome Trust anti-bullying policies, the Guardian reports.