University of Hong Kong researchers present a new method dubbed SpliceNet in Nucleic Acids Research that aims to infer isoform-specific co-expression networks from RNA-seq data. SpliceNet first looks at the expression of genes and isoforms as multivariate variables and then relies on a large dimensional trace test to uncover any pairwise dependencies and construct co-expression networks with isoform-level resolution.

Get the full story

This story is free
for registered users

Registering provides access to this and other free content.

Register now.

Already have an account?
Login Now.

Related Posts

This Week in Science

This Week in PNAS

This Week in Cell

This Week in Nature

This Week in PNAS

In Genome Research this week: multiplex genotyping of germline and somatic short tandem repeats, graph-based regularization, and more.

A lack of funding may lead more than two dozen research facilities in Australia to shut down in three months.

Researchers report that paternally inherited genes are more likely to be expressed in mice.

National Institutes of Health Director Francis Collins appears before a House subcommittee to discuss his agency's budget request.