University of Hong Kong researchers present a new method dubbed SpliceNet in Nucleic Acids Research that aims to infer isoform-specific co-expression networks from RNA-seq data. SpliceNet first looks at the expression of genes and isoforms as multivariate variables and then relies on a large dimensional trace test to uncover any pairwise dependencies and construct co-expression networks with isoform-level resolution.

Get the full story

This story is free
for registered users

Registering provides access to this and other free content.

Register now.

Already have an account?
Login Now.

Related Posts

This Week in Science

This Week in Science

This Week in Nature

This Week in PNAS

This Week in Nature

In Science this week: swapping yeast genes with human orthologs to study conservation of function, and more.

Hong Kong is using DNA phenotyping to shame litterers.

A study appearing in Cell suggests some metastatic castration-resistant prostate cancer patients could benefit from PARP inhibitor therapy.

NIH's Francis Collins writes that scientific advances are poised to help populations all over the world, but more scientists are needed to keep the momentum.