This Week in Nucleic Acids Research | GenomeWeb

In the online edition of Nucleic Acids Research, investigators from the US and Korea outlined a computational strategy for dialing down off-target interactions identified when doing loss-of-function screens with small interfering RNAs. The "Deconvolution Analysis of RNAi screening data," or DecoRNAi, method can automatically assess and diminish rates of off-target effects, according to the study's authors, who validated the strategy using data from five siRNA screens.

Get the full story

This story is free
for registered users

Registering provides access to this and other free content.

Register now.

Already have an account?
Login Now.

Related Posts

In PLOS this week: transcriptional and translational study of human cytomegalovirus interactions with host cells, spider web DNA study, and more.

The New York Stem Cell Foundation signs a lease for a new space.

Researchers gear up for an international meeting to discuss the ethics of gene editing.

In Nucleic Acids Research this week: personal genome approach to RNA-seq read alignment, hematopoietic Systems Biology Repository, and more.