A public-private team including investigators from SomaGenics, the University of California, San Francisco, Integrated DNA Technologies, and Stanford University School of Medicine shows in a paper published online in advance in Nucleic Acids Research this week that certain short shRNAs — or sshRNAs, which are "designated as L-type or R-type according to whether the loop is positioned 3′ or 5′ to the guide sequence, respectively" — require loop cleavage for optimum activity.

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Gene drives might run into biological resistance, the Economist reports.

Forensic experts exhumed painter Salvador Dalí's body to collect DNA for a paternity test, CBS News reports.

Yale Environment 360 writes that synthetic and conservation biologists aren't always on the same wavelength, but they are trying to reach an understanding.

In Science this week: full CRISPR locus integration complex structure, and more.