A public-private team including investigators from SomaGenics, the University of California, San Francisco, Integrated DNA Technologies, and Stanford University School of Medicine shows in a paper published online in advance in Nucleic Acids Research this week that certain short shRNAs — or sshRNAs, which are "designated as L-type or R-type according to whether the loop is positioned 3′ or 5′ to the guide sequence, respectively" — require loop cleavage for optimum activity.

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The Washington Post reports that a meteorologist is being considered as presidential science and technology advisor.

360Dx reports that the US Centers for Medicare & Medicaid Services would cover next-generation sequencing-based cancer panel tests.

In PNAS this week: precision medicine strategy to screen for disease risk, genome evolution in Haemophilus influenzae, and more.

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