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In a paper published online in advance in Nucleic Acids Research this week, researchers at the University of Copenhagen report having sequenced 99 percent of three unfinished gaps on human chromosome 20, and characterized those gaps epigenetically using a combination of Sanger sequencing, mate pair paired-end high-throughput sequencing, as well as chromatin, methylation and expression analyses.

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In PLOS this week: recessive mutation tied to early-onset dilated cardiomyopathy, epigenetic analysis of lung adenocarcinoma, and more.