In a paper published online in advance in Nucleic Acids Research this week, investigators at the Université du Québec à Montréal and the University of Virginia Health System report their "identification of novel proteins associated with yeast snR30 small nucleolar RNA" using an affinity purification they designed based on a "TAP-tagged Gar1 and an RNA aptamer inserted in snR30 snoRNA to selectively purify the RNP."