Researchers at the University of California, San Diego, discuss in a Nucleic Acids Research paper published online in advance this week the Saccharomyces cerevisiae gene SUS1 and, in particular, how its splicing pattern changes in response to environmental stimuli. "Unexpectedly, removal of the 3' intron is affected by splicing of the upstream intron, suggesting that cross-exon interactions influence intron removal," the UCSD researchers write.