Researchers in Madrid report that the Streptococcus pneuomoniae genome is "organized in topology-reacting gene clusters" that respond to DNA supercoiling in Nucleic Acids Research this week. The team writes that down-regulated genomic clusters are "flanked by 11-40 kb AT-rich zones that might have a putative structural function" and suggest that DNA supercoiling "controls gene expression superimposed on other kinds of more specific regulatory mechanisms."

Get the full story

This story is free
for registered users

Registering provides access to this and other free content.

Register now.

Already have an account?
Login Now.

Researchers find that a personalized medicine approach could help people who experience pain while taking statins, New Scientist reports.

US National Science Foundation is continuing its responsible research conduct training policy despite its flaws, ScienceInsider reports.

A CRISPR-themed meeting explored how the tool could and should be used, Wired reports.

In Science this week: database of proteins' effects on cancer, targeted error correction sequencing, and more.