This Week in Nature

A news story looks at how President Obama's proposed $825-billion economic stimulus bill might pan out, if passed into law. On paper, it looks good: the bill includes new funding of more than $13 billion, with the NSF receiving an additional $3 billion, the NIH, $3.5 billion, and the DOE's Office of Science, $2 billion. Critics, including Elias Zerhouni, say the bill focuses too much on short-term fixes. It's "too timid and not strategic enough in addressing the long term.

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The UK's Nuffield Council on Bioethics says genetically modifying human embryos could be morally permissible, according to the Guardian.

A new Nature Biotechnology paper reports that CRISPR-Cas9 gene editing can lead to large deletions or complex rearrangements that could be pathogenic.

The Wall Street Journal likens a prototype developed by Synthetic Genomics to a "biological fax machine."

In PNAS this week: strategy for reactivating Rett syndrome-linked MECP2, small molecules able to suppress Staphylococcus aureus virulence, and more.