This Week in Nature

A news feature in Nature this week looks at the history of defining scientific terms like paradigm shift, complexity, and epigenetics. "Popular though they are, not everyone agrees on what is meant by 'paradigm shift' or 'tipping point'," the story says.

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The US Food and Drug Administration has approved Alnylam's RNAi-based therapy Onpattro, according to Stat News.

Harvard Medical School's Seth Cassel and Cigall Kadoch argue in a Baltimore Sun op-ed that the recent TAILORx trial shows the potential of genomic-based medicine.

Researchers in the UK are working on using gene drives to control malaria-carrying mosquitoes, the Telegraph reports.

In PLOS this week: genetic architecture mediating gene expression, metabolomic patterns in multiple myeloma, and more.