This Week in Nature

In early online publication University College London researchers present findings on partial agonists, and how fully elucidating their function could make for better drug design. They say that in the case of ligand-activated ion channels, two members of the nicotinic family in particular, partial agonists cause a flipping conformational change in the channel that happens while the channel is still shut.

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An artificial intelligence-based analysis suggests a third group of ancient hominins likely interbred with human ancestors, according to Popular Mechanics.

In Science this week: reduction in bee phylogenetic diversity, and more.

The New York Times Magazine looks into paleogenomics and how it is revising what's know about human history, but also possibly ignoring lessons learned by archaeologists.

The Economist reports on Synthorx's efforts to use expanded DNA bases they generated to develop a new cancer drug.