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This Week in Nature

In early online publication University College London researchers present findings on partial agonists, and how fully elucidating their function could make for better drug design. They say that in the case of ligand-activated ion channels, two members of the nicotinic family in particular, partial agonists cause a flipping conformational change in the channel that happens while the channel is still shut.

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Mainichi reports that 43 percent of Japanese individuals said they did not want to eat agricultural products that had been modified using gene-editing tools.

Two US Department of Agriculture research departments are moving to the Kansas City area, according to the Washington Post.

Slate's Jane Hu compares some at-home genetic tests to astrology.

In PLOS this week: analysis of polygenic risk scores for skin cancer, chronic pain GWAS, and more.