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In early online publication University College London researchers present findings on partial agonists, and how fully elucidating their function could make for better drug design. They say that in the case of ligand-activated ion channels, two members of the nicotinic family in particular, partial agonists cause a flipping conformational change in the channel that happens while the channel is still shut.

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According to BBC News, the global vaccine-sharing initiative has sent its first shipment, which arrived in Ghana this week.

CNN reports that a US Food and Drug Administration document says Johnson & Johnson's SARS-CoV-2 vaccine meets the requirements to receive an Emergency Use Authorization.

Researchers in France are developing a new, fast test for SARS-CoV-2 that initial testing indicates may be highly accurate, the Guardian says.

In Cell this week: analysis of fitness patterns among SARS-CoV-2 isolates, single-cell transcriptome analysis of immune features in COVID-19, and more.