This Week in Nature

In this week's Nature, a team led by University of Geneva scientists report new insights on Down's syndrome based on an analysis of a pair of identical twins in which only one twin had an extra copy of chromosome 21. While it had been thought that most traits associated with Down's syndrome are caused by altered gene expression from the additional chromosome, the researchers show that differential gene expression is organized in domains along all chromosomes.

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The president of France's National Research Agency has resigned, according to Nature News.

A senator wants a "right-to-try" provision in the US Food and Drug Administration funding bill, but an ethicist says at Stat News that it would undermine the role of clinical trials.

In PNAS this week: red algae Porphyra umbicalis genome, deep neural network model for sequencing peptides, and more.

The Guardian's Barbara Ellen has tried out some DNA testing services to see whether they provide valuable information.