This Week in Nature

In Nature Biotechnology this week, a team led by Massachusetts Institute of Technology researchers report on the use of a gene-editing approach called CRISPR to correct a disease mutation and phenotype in mice, furthering the therapeutic potential of the technology. In the study, the scientists were able to deliver into the animals the Cas9 nuclease, along with a snippet of RNA that directed the enzyme to a specific portion of DNA where it causes double-strand breaks.

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The US National Institutes of Health and the Food and Drug Administration have proposed changing gene therapy oversight, the Associated Press reports.

Nature News reports that the Salk Institute has asked for the scope of a gender discrimination lawsuit brought against it to be narrowed.

CNBC reports that the sequencing startup Veritas aims to sequence individuals who fall at extremes.

In PLOS this week: genotyping of indigenous North African goats, program to simulate evolve and resequencing studies, and more.