This Week in Nature

In Nature this week, researchers from the Lawrence Berkeley National Laboratory report data showing that the fruit fly transcriptome is far more complex than previously thought. They examined various Drosophila cultured cell lines at different developmental stages and dissected organ systems, revealing new genes, proteins, and transcripts, including hundreds of previously unidentified long non-coding RNAs.

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In Nature this week: genomic analysis of high-grade serous ovarian cancer, and more.

The new Riken president outlines some of his plans for the institute.

The Guardian discusses whether big science projects are worth the loss of resources available for other scientific pursuits.

An NEJM update from the ClinVar team highlights the difficulties of interpreting genetic variants.