This Week in Nature

In this week's Nature, researchers from Washington University report on the discovery of a new genetic risk variant for Alzheimer's disease. The team conducted whole-exome sequencing on DNA from 29 affected individuals and 11 unaffected people, from 14 families with histories of late-onset Alzheimer's disease. It discovered a rare variant in the phospholipase D3, or PLD3, gene that was associated with a significantly greater risk of the disease.

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Consulting company McKinsey says diagnostics companies will have to combine genomic data analysis, electronic medical records, effective reimbursement strategies, and regulatory compliance in order to win.

A new report has found that researchers in Africa are still heavily dependent on funding from organizations in the US, Europe, and China, Nature News says.

An article in The Atlantic argues that the progress being made in science isn't keeping pace with the money and time being spent on research.

In Science this week: a CRISPR screen identifies sideroflexin 1 as a requisite component of one-carbon metabolism, and more.