This Week in Nature

In Nature Genetics, a team led by University of Michigan researchers report on the discovery of a long non-coding RNA that promotes aggressive prostate cancer and antagonizes the SWI/SNF chromatin-modifying complex. Based on the findings, the lncRNA, called SChLAP1, appears to contribute to the development of lethal cancer at least in part by antagonizing the tumor-suppressive functions of the SWI/SNF complex.

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Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.

The Wall Street Journal looks into the cost of new gene therapies.

An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.